Fioricet (Butalbital, Acetaminophen, Caffeine)


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Fioricet (Butalbital, Acetaminophen, Caffeine)

Common Brands: Fioricet, Esgic, Zebutal, Vtol LQ
Drug Class: Barbiturate / Analgesic / Adenosine antagonist
Generic Status: Lower-cost generic available
Availability: Prescription only 

Fioricet is a medication that contains a combination of three active ingredients: butalbital, acetaminophen, and caffeine. Butalbital is the component of Fioricet that is a barbiturate, not butalbidol.

Fioricet is primarily prescribed for the treatment of tension headaches and migraines. Here are some key points about Fioricet:

Active Ingredients: Fioricet contains three active ingredients:

Butalbital: It is a barbiturate that helps to relax muscle tension and alleviate headache pain.
Acetaminophen: It is a pain reliever and fever reducer.
Caffeine: It helps enhance the effectiveness of the other ingredients and constricts blood vessels to relieve headaches.


Floricet is available in different strengths and formulations. The recommended dosage will depend on various factors, including the severity of the headache and individual response. It is important to follow the dosage instructions provided by your healthcare professional and not exceed the prescribed limits.

Precautions and Interactions:

Fioricet may interact with other medications, including certain antidepressants, tranquilizers, and sedatives. It is crucial to inform your healthcare provider about all the medications you are taking to avoid potential drug interactions. Additionally, Fioricet contains acetaminophen, so it is important to consider the maximum daily dose of acetaminophen from all sources to avoid exceeding safe limits.

Side Effects:

Common side effects of Fioricet include drowsiness, dizziness, lightheadedness, nausea, and upset stomach. If you experience any severe or persistent side effects, contact your healthcare provider.

Dependency and Withdrawal: Fioricet contains butalbital, which is a barbiturate and has the potential for physical and psychological dependence if misused or taken for an extended period. Tapering off the medication under medical supervision is important if discontinuation is necessary.

Common Side Effects

  • Drowsiness
  • Lightheadedness
  • Dizziness
  • Loss of awareness (sedation)
  • Trouble breathing
  • Nausea
  • Vomiting
  • Stomach pain
  • Feeling “high” (intoxicated)

Other Side Effects

  • Headache
  • Shaking
  • Feeling agitated
  • Excessive sweating
  • Difficulty swallowing
  • Muscle weakness
  • Fast heart rate
  • Seizures
  • Confusion

Additional information


100 Tabs, 150 Tabs, 180 Tabs


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